Health Canada is currently reviewing regulations for pesticides in Canada, and three UBC researchers say regulators might want to consider what happened in Japan. A lake in Shimane Prefecture has seen its commercial fishery collapse by more than 90 per cent since 1993, when insecticides known as neonicotinoids were first introduced to the area. It just so happens that zooplankton—the tiny creatures in the water that fish feed on—declined by 83 per cent during the same period.